An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.
Two new studies are pointing the way toward round-the-clock personalized care for people with Parkinson's disease through an implanted device that can treat movement problems during the day and insomnia at night.
Using machine learning to analyze video recordings of individuals performing simple movements, researchers developed a method to automaticaly quanitfy motor systems in early-stage Parkinson's disease and other movement disorders.
A research team examined the effect of Ecklonia cava polyphenols on the prevention of Parkinson's disease. It was found that the oral intake of the seaweed antioxidants restores motor function and protects dopaminergic neurons in model mice, while cellular experiments revealed the biochemical interaction of their preventive effect.