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Neuronal circuits in the brain 'sense' our inner state
on July 15, 2020 at 3:14 pm
How decisions are made and how behavior is controlled is one of the most important questions in neuroscience. The neurotransmitter dopamine plays a central role in all of this. Scientists looked into the role that dopamine plays in the decision-making process and in controlling movement.
One-time treatment generates new neurons, eliminates Parkinson's disease in mice
on June 25, 2020 at 2:25 pm
Researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice's Parkinson's disease symptoms disappear.
Disrupted circadian rhythms linked to later Parkinson's diagnoses
on June 15, 2020 at 6:28 pm
Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study.
Solving a Parkinson's disease puzzle through protein design
on June 11, 2020 at 1:41 pm
Scientists have developed a computational protein design approach, and used it to obtain the first ever high-resolution structure of an activated dopamine receptor in its natural cell membrane environment. The breakthrough will open up a new dimension in drug discovery for Parkinson's disease and perhaps other disorders.
Molecular pair offers potential for Parkinson's treatment
on May 27, 2020 at 4:34 pm
A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson's disease, a study has found.